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The Use of Spreadsheets for Pharmacokinetic Simulations
The use of simple spreadsheets is described to create simulations of complex pharmacokinetic phenomena. The basics of spreadsheets are first described and are developed to demonstrate classical pharmacokinetics without the use of differential or integral calculus. Using standard spreadsheet commands...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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TheScientificWorldJOURNAL
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974879/ https://www.ncbi.nlm.nih.gov/pubmed/12806111 http://dx.doi.org/10.1100/tsw.2003.02 |
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author | Chamberlain, Joseph |
author_facet | Chamberlain, Joseph |
author_sort | Chamberlain, Joseph |
collection | PubMed |
description | The use of simple spreadsheets is described to create simulations of complex pharmacokinetic phenomena. The basics of spreadsheets are first described and are developed to demonstrate classical pharmacokinetics without the use of differential or integral calculus. Using standard spreadsheet commands, the technique is shown to be applicable to the full range of advanced pharmacokinetic simulations. Demonstrations of the effect of a variety of physiological eventualities are included to show the versatility of the technique. The technique is very simple to use and is always in the complete control of the modeller. |
format | Online Article Text |
id | pubmed-5974879 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2003 |
publisher | TheScientificWorldJOURNAL |
record_format | MEDLINE/PubMed |
spelling | pubmed-59748792018-06-10 The Use of Spreadsheets for Pharmacokinetic Simulations Chamberlain, Joseph ScientificWorldJournal Methods Paper The use of simple spreadsheets is described to create simulations of complex pharmacokinetic phenomena. The basics of spreadsheets are first described and are developed to demonstrate classical pharmacokinetics without the use of differential or integral calculus. Using standard spreadsheet commands, the technique is shown to be applicable to the full range of advanced pharmacokinetic simulations. Demonstrations of the effect of a variety of physiological eventualities are included to show the versatility of the technique. The technique is very simple to use and is always in the complete control of the modeller. TheScientificWorldJOURNAL 2003-04-21 /pmc/articles/PMC5974879/ /pubmed/12806111 http://dx.doi.org/10.1100/tsw.2003.02 Text en Copyright © 2003 Joseph Chamberlain. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Methods Paper Chamberlain, Joseph The Use of Spreadsheets for Pharmacokinetic Simulations |
title | The Use of Spreadsheets for Pharmacokinetic Simulations |
title_full | The Use of Spreadsheets for Pharmacokinetic Simulations |
title_fullStr | The Use of Spreadsheets for Pharmacokinetic Simulations |
title_full_unstemmed | The Use of Spreadsheets for Pharmacokinetic Simulations |
title_short | The Use of Spreadsheets for Pharmacokinetic Simulations |
title_sort | use of spreadsheets for pharmacokinetic simulations |
topic | Methods Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974879/ https://www.ncbi.nlm.nih.gov/pubmed/12806111 http://dx.doi.org/10.1100/tsw.2003.02 |
work_keys_str_mv | AT chamberlainjoseph theuseofspreadsheetsforpharmacokineticsimulations AT chamberlainjoseph useofspreadsheetsforpharmacokineticsimulations |