Cargando…
Resveratrol attenuates testicular apoptosis in type 1 diabetic mice: Role of Akt-mediated Nrf2 activation and p62-dependent Keap1 degradation
Infertility is a common complication in diabetic men, mainly due to the loss of germ cells by apoptotic cell death. However, effective and safe approaches to prevent diabetic induction of testicular apoptosis for diabetic patients have not been available. Resveratrol (RSV), a group of compounds call...
Autores principales: | Zhao, Yuguang, Song, Wenjing, Wang, Zhenyu, Wang, Zongqiang, Jin, Xing, Xu, Jiancheng, Bai, Ling, Li, Yuying, Cui, Jiuwei, Cai, Lu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975057/ https://www.ncbi.nlm.nih.gov/pubmed/29154192 http://dx.doi.org/10.1016/j.redox.2017.11.007 |
Ejemplares similares
-
Lycopene prevents carcinogen-induced cutaneous tumor by enhancing activation of the Nrf2 pathway through p62-triggered autophagic Keap1 degradation
por: Wang, Siliang, et al.
Publicado: (2020) -
SMURF1 attenuates endoplasmic reticulum stress by promoting the degradation of KEAP1 to activate NRF2 antioxidant pathway
por: Dong, Lei, et al.
Publicado: (2023) -
Negative Regulation of the Keap1-Nrf2 Pathway by a p62/Sqstm1 Splicing Variant
por: Kageyama, Shun, et al.
Publicado: (2018) -
The hypertension drug, verapamil, activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity
por: Lee, Da Hyun, et al.
Publicado: (2017) -
Combination of Metformin and Sorafenib Induces Ferroptosis of Hepatocellular Carcinoma Through p62-Keap1-Nrf2 Pathway
por: Tang, Kezhong, et al.
Publicado: (2022)