A glutaredoxin in the mitochondrial intermembrane space has stage-specific functions in the thermo-tolerance and proliferation of African trypanosomes

Trypanosoma brucei glutaredoxin 2 (Grx2) is a dithiol glutaredoxin that is specifically located in the mitochondrial intermembrane space. Bloodstream form parasites lacking Grx2 or both, Grx2 and the cytosolic Grx1, are viable in vitro and infectious to mice suggesting that neither oxidoreductase is...

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Detalles Bibliográficos
Autores principales: Ebersoll, Samantha, Musunda, Blessing, Schmenger, Torsten, Dirdjaja, Natalie, Bonilla, Mariana, Manta, Bruno, Ulrich, Kathrin, Comini, Marcelo A., Krauth-Siegel, R. Luise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975080/
https://www.ncbi.nlm.nih.gov/pubmed/29413965
http://dx.doi.org/10.1016/j.redox.2018.01.011

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