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Neuronal Dysfunction and Behavioral Abnormalities Are Evoked by Neural Cells and Aggravated by Inflammatory Microglia in Peroxisomal β-Oxidation Deficiency

It is becoming evident that microglia, the resident immune cells of the central nervous system (CNS), are active contributors in neurological disorders. Nevertheless, the impact of microgliosis on neuropathology, behavior and clinical decline in neuropathological conditions remains elusive. A mouse...

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Detalles Bibliográficos
Autores principales: Beckers, Lien, Stroobants, Stijn, D’Hooge, Rudi, Baes, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975114/
https://www.ncbi.nlm.nih.gov/pubmed/29892213
http://dx.doi.org/10.3389/fncel.2018.00136