Cargando…

Lipophilic ester and amide derivatives of rosmarinic acid protect cells against H(2)O(2)-induced DNA damage and apoptosis: The potential role of intracellular accumulation and labile iron chelation

Phenolic acids represent abundant components contained in human diet. However, the negative charge in their carboxylic group limits their capacity to diffuse through biological membranes, thus hindering their access to cell interior. In order to promote the diffusion of rosmarinic acid through biolo...

Descripción completa

Detalles Bibliográficos
Autores principales: Gerogianni, Paraskevi S., Chatziathanasiadou, Maria V., Diamantis, Dimitrios A., Tzakos, Andreas G., Galaris, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975196/
https://www.ncbi.nlm.nih.gov/pubmed/29413966
http://dx.doi.org/10.1016/j.redox.2018.01.014