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Inhibition of apoptosis by Rv2456c through Nuclear factor-κB extends the survival of Mycobacterium tuberculosis

Mycobacterium tuberculosis, the causative agent of tuberculosis, is an intracellular pathogen with several survival mechanisms aimed at subverting the host immune system. Apoptosis has been shown to be mycobactericidal, to activate CD8(+) T cells, and to be modulated by mycobacterial proteins. Since...

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Detalles Bibliográficos
Autores principales: Jurcic Smith, Kristen L., Lee, Sunhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975360/
https://www.ncbi.nlm.nih.gov/pubmed/27931684
http://dx.doi.org/10.1016/j.ijmyco.2016.06.018