An innovative diagnostic technology for the codon mutation C580Y in kelch13 of Plasmodium falciparum with MinION nanopore sequencer

BACKGROUND: The recent spread of artemisinin (ART)-resistant Plasmodium falciparum represents an emerging global threat to public health. In Southeast Asia, the C580Y mutation of kelch13 (k13) is the dominant mutation of ART-resistant P. falciparum. Therefore, a simple method for the detection of C5...

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Detalles Bibliográficos
Autores principales: Imai, Kazuo, Tarumoto, Norihito, Runtuwene, Lucky Ronald, Sakai, Jun, Hayashida, Kyoko, Eshita, Yuki, Maeda, Ryuichiro, Tuda, Josef, Ohno, Hideaki, Murakami, Takashi, Maesaki, Shigefumi, Suzuki, Yutaka, Yamagishi, Junya, Maeda, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975513/
https://www.ncbi.nlm.nih.gov/pubmed/29843734
http://dx.doi.org/10.1186/s12936-018-2362-x

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