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Stratification of ovarian tumor pathology by expression of programmed cell death-1 (PD-1) and PD-ligand- 1 (PD-L1) in ovarian cancer

BACKGROUND: Ovarian cancer is the major cause of death among gynecologic cancers with 75% of patients diagnosed with advanced disease, and only 20% of these patients having a survival duration of five years. Treatments blocking immune checkpoint molecules, programmed cell death (PD-1) or its ligand...

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Detalles Bibliográficos
Autores principales: Drakes, Maureen L., Mehrotra, Swati, Aldulescu, Monica, Potkul, Ronald K., Liu, Yueying, Grisoli, Anne, Joyce, Cara, O’Brien, Timothy E., Stack, M. Sharon, Stiff, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975524/
https://www.ncbi.nlm.nih.gov/pubmed/29843813
http://dx.doi.org/10.1186/s13048-018-0414-z