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miR-519a enhances chemosensitivity and promotes autophagy in glioblastoma by targeting STAT3/Bcl2 signaling pathway

BACKGROUND: Chemoresistance to temozolomide (TMZ) is a major challenge in the treatment of glioblastoma (GBM). We previously found that miR-519a functions as a tumor suppressor in glioma by targeting the signal transducer and activator of transcription 3 (STAT3)-mediated autophagy oncogenic pathway....

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Detalles Bibliográficos
Autores principales:	Li, Hong, Chen, Lei, Li, Jun-jie, Zhou, Qiang, Huang, Annie, Liu, Wei-wen, Wang, Ke, Gao, Liang, Qi, Song-tao, Lu, Yun-tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975545/ https://www.ncbi.nlm.nih.gov/pubmed/29843746 http://dx.doi.org/10.1186/s13045-018-0618-0

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