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Modeling the neuron as a nanocommunication system to identify spatiotemporal molecular events in neurodegenerative disease
AIM: In tauopathies such as Alzheimer’s disease (AD), molecular changes spanning multiple subcellular compartments of the neuron contribute to neurodegeneration and altered axonal signaling. Computational modeling of end-to-end linked events benefit mechanistic analysis and can be informative to und...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975603/ https://www.ncbi.nlm.nih.gov/pubmed/29872297 http://dx.doi.org/10.2147/IJN.S152664 |