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Rare copy number variants analysis identifies novel candidate genes in heterotaxy syndrome patients with congenital heart defects

BACKGROUND: Heterotaxy (Htx) syndrome comprises a class of congenital disorders resulting from malformations in left-right body patterning. Approximately 90% of patients with heterotaxy have serious congenital heart diseases; as a result, the survival rate and outcomes of Htx patients are not satisf...

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Detalles Bibliográficos
Autores principales:	Liu, Chunjie, Cao, Ruixue, Xu, Yuejuan, Li, Tingting, Li, Fen, Chen, Sun, Xu, Rang, Sun, Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975672/ https://www.ncbi.nlm.nih.gov/pubmed/29843777 http://dx.doi.org/10.1186/s13073-018-0549-y

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