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MIG-6 suppresses endometrial epithelial cell proliferation by inhibiting phospho-AKT
BACKGROUND: Aberrant hyperactivation of epithelial proliferation, AKT signaling, and association with unopposed estrogen (E2) exposure is the most common endometrial cancer dysfunction. In the normal uterus, progesterone (P4) inhibits proliferation by coordinating stromal-epithelial cross-talk, whic...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975686/ https://www.ncbi.nlm.nih.gov/pubmed/29843645 http://dx.doi.org/10.1186/s12885-018-4502-7 |