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MIG-6 suppresses endometrial epithelial cell proliferation by inhibiting phospho-AKT

BACKGROUND: Aberrant hyperactivation of epithelial proliferation, AKT signaling, and association with unopposed estrogen (E2) exposure is the most common endometrial cancer dysfunction. In the normal uterus, progesterone (P4) inhibits proliferation by coordinating stromal-epithelial cross-talk, whic...

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Detalles Bibliográficos
Autores principales:	Yoo, Jung-Yoon, Kang, Hee-Bum, Broaddus, Russell R., Risinger, John I., Choi, Kyung-Chul, Kim, Tae Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975686/ https://www.ncbi.nlm.nih.gov/pubmed/29843645 http://dx.doi.org/10.1186/s12885-018-4502-7

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