Cationic porphyrins are tunable gatekeepers of the 20S proteasome

The 20S proteasome is a barrel-shaped enzymatic assembly playing a critical role in proteome maintenance. Access of proteasome substrates to the catalytic chamber is finely regulated through gating mechanisms which involve aromatic and negatively charged residues located at the N-terminal tails of α...

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Detalles Bibliográficos
Autores principales: Santoro, Anna M., Cunsolo, Alessandra, D'Urso, Alessandro, Sbardella, Diego, Tundo, Grazia R., Ciaccio, Chiara, Coletta, Massimiliano, Diana, Donatella, Fattorusso, Roberto, Persico, Marco, Di Dato, Antonio, Fattorusso, Caterina, Milardi, Danilo, Purrello, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975898/
https://www.ncbi.nlm.nih.gov/pubmed/29910886
http://dx.doi.org/10.1039/c5sc03312h

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