N (6)-Methyladenine hinders RNA- and DNA-directed DNA synthesis: application in human rRNA methylation analysis of clinical specimens

N (6)-Methyladenine (m(6)A) is the most abundant internal modification on mammalian mRNA. Very recently, m(6)A has been reported as a potentially important ‘epigenetic’ mark in eukaryotes. Until now, site-specific detection of m(6)A is technically very challenging. Here, we first reveal that m(6)A s...

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Detalles Bibliográficos
Autores principales: Wang, Shaoru, Wang, Jiaqi, Zhang, Xiaoe, Fu, Boshi, Song, Yanyan, Ma, Pei, Gu, Kai, Zhou, Xin, Zhang, Xiaolian, Tian, Tian, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975930/
https://www.ncbi.nlm.nih.gov/pubmed/29910902
http://dx.doi.org/10.1039/c5sc02902c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975930/
https://www.ncbi.nlm.nih.gov/pubmed/29910902
http://dx.doi.org/10.1039/c5sc02902c

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