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Higher-order structural interrogation of antibodies using middle-down hydrogen/deuterium exchange mass spectrometry
Although X-ray crystallography is the “gold standard” method for protein higher-order structure analysis, the challenges of antibody crystallization and the time-consuming data analysis involved make this technique unsuitable for routine structural studies of antibodies. In addition, crystallography...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975933/ https://www.ncbi.nlm.nih.gov/pubmed/29910905 http://dx.doi.org/10.1039/c5sc03420e |