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Dendritic potassium channel dysfunction may contribute to dendrite degeneration in spinocerebellar ataxia type 1
Purkinje neuron dendritic degeneration precedes cell loss in cerebellar ataxia, but the basis for dendritic vulnerability in ataxia remains poorly understood. Recent work has suggested that potassium (K(+)) channel dysfunction and consequent spiking abnormalities contribute to Purkinje neuron degene...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976172/ https://www.ncbi.nlm.nih.gov/pubmed/29847609 http://dx.doi.org/10.1371/journal.pone.0198040 |