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Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections

BACKGROUND/AIMS: Typical approach for increasing apheresis platelet collections is to recruit new donors. Here, we investigated the effectiveness of an alternative strategy: optimizing donor scheduling, prior to recruitment, at a hospital-based blood donor center. METHODS: Analysis of collections, d...

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Autores principales: Lokhandwala, Parvez M., Shike, Hiroko, Wang, Ming, Domen, Ronald E., George, Melissa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976181/
https://www.ncbi.nlm.nih.gov/pubmed/29847596
http://dx.doi.org/10.1371/journal.pone.0198062
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author Lokhandwala, Parvez M.
Shike, Hiroko
Wang, Ming
Domen, Ronald E.
George, Melissa R.
author_facet Lokhandwala, Parvez M.
Shike, Hiroko
Wang, Ming
Domen, Ronald E.
George, Melissa R.
author_sort Lokhandwala, Parvez M.
collection PubMed
description BACKGROUND/AIMS: Typical approach for increasing apheresis platelet collections is to recruit new donors. Here, we investigated the effectiveness of an alternative strategy: optimizing donor scheduling, prior to recruitment, at a hospital-based blood donor center. METHODS: Analysis of collections, during the 89 consecutive months since opening of donor center, was performed. Linear regression and segmented time-series analyses were performed to calculate growth rates of collections and to test for statistical differences, respectively. RESULTS: Pre-intervention donor scheduling capacity was 39/month. In the absence of active donor recruitment, during the first 29 months, the number of collections rose gradually to 24/month (growth-rate of 0.70/month). However, between month-30 and -55, collections exhibited a plateau at 25.6 ± 3.0 (growth-rate of -0.09/month) (p<0.0001). This plateau-phase coincided with donor schedule approaching saturation (65.6 ± 7.6% schedule booked). Scheduling capacity was increased by following two interventions: adding an apheresis instrument (month-56) and adding two more collection days/week (month-72). Consequently, the scheduling capacity increased to 130/month. Post-interventions, apheresis platelet collections between month-56 and -81 exhibited a spontaneous renewed growth at a rate of 0.62/month (p<0.0001), in absence of active donor recruitment. Active donor recruitment in month-82 and -86, when the donor schedule had been optimized to accommodate further growth, resulted in a dramatic but transient surge in collections. CONCLUSION: Apheresis platelet collections plateau at nearly 2/3(rd) of the scheduling capacity. Optimizing the scheduling capacity prior to active donor recruitment is an effective strategy to increase platelet collections at a hospital-based donor center.
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spelling pubmed-59761812018-06-17 Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections Lokhandwala, Parvez M. Shike, Hiroko Wang, Ming Domen, Ronald E. George, Melissa R. PLoS One Research Article BACKGROUND/AIMS: Typical approach for increasing apheresis platelet collections is to recruit new donors. Here, we investigated the effectiveness of an alternative strategy: optimizing donor scheduling, prior to recruitment, at a hospital-based blood donor center. METHODS: Analysis of collections, during the 89 consecutive months since opening of donor center, was performed. Linear regression and segmented time-series analyses were performed to calculate growth rates of collections and to test for statistical differences, respectively. RESULTS: Pre-intervention donor scheduling capacity was 39/month. In the absence of active donor recruitment, during the first 29 months, the number of collections rose gradually to 24/month (growth-rate of 0.70/month). However, between month-30 and -55, collections exhibited a plateau at 25.6 ± 3.0 (growth-rate of -0.09/month) (p<0.0001). This plateau-phase coincided with donor schedule approaching saturation (65.6 ± 7.6% schedule booked). Scheduling capacity was increased by following two interventions: adding an apheresis instrument (month-56) and adding two more collection days/week (month-72). Consequently, the scheduling capacity increased to 130/month. Post-interventions, apheresis platelet collections between month-56 and -81 exhibited a spontaneous renewed growth at a rate of 0.62/month (p<0.0001), in absence of active donor recruitment. Active donor recruitment in month-82 and -86, when the donor schedule had been optimized to accommodate further growth, resulted in a dramatic but transient surge in collections. CONCLUSION: Apheresis platelet collections plateau at nearly 2/3(rd) of the scheduling capacity. Optimizing the scheduling capacity prior to active donor recruitment is an effective strategy to increase platelet collections at a hospital-based donor center. Public Library of Science 2018-05-30 /pmc/articles/PMC5976181/ /pubmed/29847596 http://dx.doi.org/10.1371/journal.pone.0198062 Text en © 2018 Lokhandwala et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Lokhandwala, Parvez M.
Shike, Hiroko
Wang, Ming
Domen, Ronald E.
George, Melissa R.
Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections
title Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections
title_full Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections
title_fullStr Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections
title_full_unstemmed Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections
title_short Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections
title_sort optimizing donor scheduling before recruitment: an effective approach to increasing apheresis platelet collections
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976181/
https://www.ncbi.nlm.nih.gov/pubmed/29847596
http://dx.doi.org/10.1371/journal.pone.0198062
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