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Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections
BACKGROUND/AIMS: Typical approach for increasing apheresis platelet collections is to recruit new donors. Here, we investigated the effectiveness of an alternative strategy: optimizing donor scheduling, prior to recruitment, at a hospital-based blood donor center. METHODS: Analysis of collections, d...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976181/ https://www.ncbi.nlm.nih.gov/pubmed/29847596 http://dx.doi.org/10.1371/journal.pone.0198062 |
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author | Lokhandwala, Parvez M. Shike, Hiroko Wang, Ming Domen, Ronald E. George, Melissa R. |
author_facet | Lokhandwala, Parvez M. Shike, Hiroko Wang, Ming Domen, Ronald E. George, Melissa R. |
author_sort | Lokhandwala, Parvez M. |
collection | PubMed |
description | BACKGROUND/AIMS: Typical approach for increasing apheresis platelet collections is to recruit new donors. Here, we investigated the effectiveness of an alternative strategy: optimizing donor scheduling, prior to recruitment, at a hospital-based blood donor center. METHODS: Analysis of collections, during the 89 consecutive months since opening of donor center, was performed. Linear regression and segmented time-series analyses were performed to calculate growth rates of collections and to test for statistical differences, respectively. RESULTS: Pre-intervention donor scheduling capacity was 39/month. In the absence of active donor recruitment, during the first 29 months, the number of collections rose gradually to 24/month (growth-rate of 0.70/month). However, between month-30 and -55, collections exhibited a plateau at 25.6 ± 3.0 (growth-rate of -0.09/month) (p<0.0001). This plateau-phase coincided with donor schedule approaching saturation (65.6 ± 7.6% schedule booked). Scheduling capacity was increased by following two interventions: adding an apheresis instrument (month-56) and adding two more collection days/week (month-72). Consequently, the scheduling capacity increased to 130/month. Post-interventions, apheresis platelet collections between month-56 and -81 exhibited a spontaneous renewed growth at a rate of 0.62/month (p<0.0001), in absence of active donor recruitment. Active donor recruitment in month-82 and -86, when the donor schedule had been optimized to accommodate further growth, resulted in a dramatic but transient surge in collections. CONCLUSION: Apheresis platelet collections plateau at nearly 2/3(rd) of the scheduling capacity. Optimizing the scheduling capacity prior to active donor recruitment is an effective strategy to increase platelet collections at a hospital-based donor center. |
format | Online Article Text |
id | pubmed-5976181 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-59761812018-06-17 Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections Lokhandwala, Parvez M. Shike, Hiroko Wang, Ming Domen, Ronald E. George, Melissa R. PLoS One Research Article BACKGROUND/AIMS: Typical approach for increasing apheresis platelet collections is to recruit new donors. Here, we investigated the effectiveness of an alternative strategy: optimizing donor scheduling, prior to recruitment, at a hospital-based blood donor center. METHODS: Analysis of collections, during the 89 consecutive months since opening of donor center, was performed. Linear regression and segmented time-series analyses were performed to calculate growth rates of collections and to test for statistical differences, respectively. RESULTS: Pre-intervention donor scheduling capacity was 39/month. In the absence of active donor recruitment, during the first 29 months, the number of collections rose gradually to 24/month (growth-rate of 0.70/month). However, between month-30 and -55, collections exhibited a plateau at 25.6 ± 3.0 (growth-rate of -0.09/month) (p<0.0001). This plateau-phase coincided with donor schedule approaching saturation (65.6 ± 7.6% schedule booked). Scheduling capacity was increased by following two interventions: adding an apheresis instrument (month-56) and adding two more collection days/week (month-72). Consequently, the scheduling capacity increased to 130/month. Post-interventions, apheresis platelet collections between month-56 and -81 exhibited a spontaneous renewed growth at a rate of 0.62/month (p<0.0001), in absence of active donor recruitment. Active donor recruitment in month-82 and -86, when the donor schedule had been optimized to accommodate further growth, resulted in a dramatic but transient surge in collections. CONCLUSION: Apheresis platelet collections plateau at nearly 2/3(rd) of the scheduling capacity. Optimizing the scheduling capacity prior to active donor recruitment is an effective strategy to increase platelet collections at a hospital-based donor center. Public Library of Science 2018-05-30 /pmc/articles/PMC5976181/ /pubmed/29847596 http://dx.doi.org/10.1371/journal.pone.0198062 Text en © 2018 Lokhandwala et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Lokhandwala, Parvez M. Shike, Hiroko Wang, Ming Domen, Ronald E. George, Melissa R. Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections |
title | Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections |
title_full | Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections |
title_fullStr | Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections |
title_full_unstemmed | Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections |
title_short | Optimizing donor scheduling before recruitment: An effective approach to increasing apheresis platelet collections |
title_sort | optimizing donor scheduling before recruitment: an effective approach to increasing apheresis platelet collections |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976181/ https://www.ncbi.nlm.nih.gov/pubmed/29847596 http://dx.doi.org/10.1371/journal.pone.0198062 |
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