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Generation of transgenic chickens expressing the human erythropoietin (hEPO) gene in an oviduct-specific manner: Production of transgenic chicken eggs containing human erythropoietin in egg whites
The transgenic chicken has been considered as a prospective bioreactor for large-scale production of costly pharmaceutical proteins. In the present study, we report successful generation of transgenic hens that lay eggs containing a high concentration of human erythropoietin (hEPO) in the ovalbumin....
Autores principales: | Kwon, Mo Sun, Koo, Bon Chul, Kim, Dohyang, Nam, Yu Hwa, Cui, Xiang-Shun, Kim, Nam-Hyung, Kim, Teoan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976184/ https://www.ncbi.nlm.nih.gov/pubmed/29847554 http://dx.doi.org/10.1371/journal.pone.0194721 |
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