Integration of genetic and metabolic features related to sialic acid metabolism distinguishes human breast cell subtypes

In this report we use ‘high-flux’ tributanoyl-modified N-acetylmannosamine (ManNAc) analogs with natural N-acetyl as well as non-natural azido- and alkyne N-acyl groups (specifically, 1,3,4-O-Bu(3)ManNAc, 1,3,4-O-Bu(3)ManNAz, and 1,3,4-O-Bu(3)ManNAl respectively) to probe intracellular sialic acid m...

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Detalles Bibliográficos
Autores principales: Saeui, Christopher T., Nairn, Alison V., Galizzi, Melina, Douville, Christopher, Gowda, Prateek, Park, Marian, Dharmarha, Vrinda, Shah, Sagar R., Clarke, Amelia, Austin, Melissa, Moremen, Kelley W., Yarema, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976204/
https://www.ncbi.nlm.nih.gov/pubmed/29847599
http://dx.doi.org/10.1371/journal.pone.0195812

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