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Causal Impact of Type 2 Diabetes Mellitus on Cerebral Small Vessel Disease: A Mendelian Randomization Analysis

BACKGROUND AND PURPOSE—: The relationship between type 2 diabetes mellitus (T2D) and cerebral small vessel disease (CSVD) is unclear. We aimed to examine the causal effect of T2D, fasting glucose levels, and higher insulin resistance on CSVD using Mendelian randomization. METHODS—: Five CSVD phenoty...

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Detalles Bibliográficos
Autores principales:	Liu, Junfeng, Rutten-Jacobs, Loes, Liu, Ming, Markus, Hugh S., Traylor, Matthew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2018
Materias:	Original Contributions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976219/ https://www.ncbi.nlm.nih.gov/pubmed/29686024 http://dx.doi.org/10.1161/STROKEAHA.117.020536

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