Hyperpigmentation with Capecitabine: Part of Hand-Foot Syndrome or a Separate Entity?

Capecitabine has several side effects, most common of which is Hand-Foot syndrome (HFS); however, less frequently reported is capecitabine-associated hyperpigmentation. The hyperpigmentation associated with this drug has been documented to involve the hands and feet and, less commonly, the mucous me...

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Detalles Bibliográficos
Autores principales: Caprez, Jennifer, Rahim, Umar, Ansari, Amna, Lodhi, Muhammad Uzair, Rahim, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Family/General Practice
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976272/
https://www.ncbi.nlm.nih.gov/pubmed/29854572
http://dx.doi.org/10.7759/cureus.2397
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author Caprez, Jennifer
Rahim, Umar
Ansari, Amna
Lodhi, Muhammad Uzair
Rahim, Mustafa
author_facet Caprez, Jennifer
Rahim, Umar
Ansari, Amna
Lodhi, Muhammad Uzair
Rahim, Mustafa
author_sort Caprez, Jennifer
collection PubMed
description Capecitabine has several side effects, most common of which is Hand-Foot syndrome (HFS); however, less frequently reported is capecitabine-associated hyperpigmentation. The hyperpigmentation associated with this drug has been documented to involve the hands and feet and, less commonly, the mucous membranes of the mouth. To our knowledge, it has never been documented to involve the face. We report a case of a patient with capecitabine-induced Hand-Foot Syndrome (HFS), who also presented with hyperpigmentation of the hands, feet, oral mucosa, and face.
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spelling pubmed-59762722018-05-31 Hyperpigmentation with Capecitabine: Part of Hand-Foot Syndrome or a Separate Entity? Caprez, Jennifer Rahim, Umar Ansari, Amna Lodhi, Muhammad Uzair Rahim, Mustafa Cureus Family/General Practice Capecitabine has several side effects, most common of which is Hand-Foot syndrome (HFS); however, less frequently reported is capecitabine-associated hyperpigmentation. The hyperpigmentation associated with this drug has been documented to involve the hands and feet and, less commonly, the mucous membranes of the mouth. To our knowledge, it has never been documented to involve the face. We report a case of a patient with capecitabine-induced Hand-Foot Syndrome (HFS), who also presented with hyperpigmentation of the hands, feet, oral mucosa, and face. Cureus 2018-03-30 /pmc/articles/PMC5976272/ /pubmed/29854572 http://dx.doi.org/10.7759/cureus.2397 Text en Copyright © 2018, Caprez et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Family/General Practice
Caprez, Jennifer
Rahim, Umar
Ansari, Amna
Lodhi, Muhammad Uzair
Rahim, Mustafa
Hyperpigmentation with Capecitabine: Part of Hand-Foot Syndrome or a Separate Entity?
title Hyperpigmentation with Capecitabine: Part of Hand-Foot Syndrome or a Separate Entity?
title_full Hyperpigmentation with Capecitabine: Part of Hand-Foot Syndrome or a Separate Entity?
title_fullStr Hyperpigmentation with Capecitabine: Part of Hand-Foot Syndrome or a Separate Entity?
title_full_unstemmed Hyperpigmentation with Capecitabine: Part of Hand-Foot Syndrome or a Separate Entity?
title_short Hyperpigmentation with Capecitabine: Part of Hand-Foot Syndrome or a Separate Entity?
title_sort hyperpigmentation with capecitabine: part of hand-foot syndrome or a separate entity?
topic Family/General Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976272/
https://www.ncbi.nlm.nih.gov/pubmed/29854572
http://dx.doi.org/10.7759/cureus.2397
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