MYB induces the expression of the oncogenic corepressor SKI in acute myeloid leukemia

Acute myeloid leukemia (AML) arises through clonal expansion of transformed myeloid progenitor cells. The SKI proto-oncogene is highly upregulated in different solid tumors and leukemic cells, but little is known about its transcriptional regulation during leukemogenesis. MYB is an important hematop...

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Detalles Bibliográficos
Autores principales: Frech, Miriam, Teichler, Sabine, Feld, Christine, Bouchard, Caroline, Berberich, Hannah, Sorg, Katharina, Mernberger, Marco, Bullinger, Lars, Bauer, Uta-Maria, Neubauer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976475/
https://www.ncbi.nlm.nih.gov/pubmed/29854289
http://dx.doi.org/10.18632/oncotarget.25051

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