Cargando…
PSA-selective activation of cytotoxic human serine proteases within the tumor microenvironment as a therapeutic strategy to target prostate cancer
Prostate cancer is the most diagnosed malignancy and the second leading cause of cancer-related death in American men. While localized therapy is highly curative, treatments for metastatic prostate cancer are largely palliative. Thus, new innovative therapies are needed to target metastatic tumors....
Autores principales: | Rogers, Oliver C., Anthony, Lizamma, Rosen, D. Marc, Brennen, W. Nathaniel, Denmeade, Samuel R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976476/ https://www.ncbi.nlm.nih.gov/pubmed/29854290 http://dx.doi.org/10.18632/oncotarget.25091 |
Ejemplares similares
-
Albumin-linked prostate-specific antigen-activated thapsigargin- and niclosamide-based molecular grenades targeting the microenvironment in metastatic castration-resistant prostate cancer
por: Akinboye, Emmanuel S., et al.
Publicado: (2019) -
Quantification of Mesenchymal Stem Cells (MSCs) at Sites of Human Prostate Cancer
por: Brennen, W. Nathaniel, et al.
Publicado: (2012) -
Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate
por: Brennen, W. Nathaniel, et al.
Publicado: (2017) -
The effect of the frequency and duration of prostate specific antigen (PSA) measurement on PSA doubling time calculations in men with biochemically recurrent prostate cancer
por: Paller, CJ, et al.
Publicado: (2013) -
Mipsagargin: The Beginning—Not the End—of Thapsigargin Prodrug-Based Cancer Therapeutics
por: Isaacs, John T., et al.
Publicado: (2021)