Cargando…
Anti-podocalyxin antibody exerts antitumor effects via antibody-dependent cellular cytotoxicity in mouse xenograft models of oral squamous cell carcinoma
Podocalyxin (PODXL) overexpression is associated with progression, metastasis, and poor outcomes in cancers. We recently produced the novel anti-PODXL monoclonal antibody (mAb) PcMab-47 (IgG(1), kappa). Herein, we engineered PcMab-47 into 47-mG(2a), a mouse IgG(2a)-type mAb, to add antibody-dependen...
| Autores principales: | , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976479/ https://www.ncbi.nlm.nih.gov/pubmed/29854293 http://dx.doi.org/10.18632/oncotarget.25132 |