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Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer

Nitric oxide (NO) plays an established role in numerous physiological and pathological processes, but the specific cellular sources of NO in disease pathogenesis remain unclear, preventing the implementation of NO-related therapy. Argininosuccinate lyase (ASL) is the only enzyme able to produce argi...

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Detalles Bibliográficos
Autores principales: Stettner, Noa, Rosen, Chava, Bernshtein, Biana, Gur-Cohen, Shiri, Frug, Julia, Silberman, Alon, Sarver, Alona, Carmel-Neiderman, Narin N., Eilam, Raya, Biton, Inbal, Pevsner-Fischer, Meirav, Zmora, Niv, Brandis, Alexander, Bahar Halpern, Keren, Mazkereth, Ram, di Bernardo, Diego, Brunetti-Pierri, Nicola, Premkumar, Muralidhar H., Dank, Gillian, Nagamani, Sandesh C.S., Jung, Steffen, Harmelin, Alon, Erez, Ayelet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976577/
https://www.ncbi.nlm.nih.gov/pubmed/29768197
http://dx.doi.org/10.1016/j.celrep.2018.04.053