Palladium-Catalyzed Synthesis of Aldehydes from Aryl Iodides and Formic acid with Propylphosphonic Anhydride as the Activator

An interesting palladium-catalyzed carbonylative procedure for the synthesis of aromatic aldehydes from aryl iodides has been developed. By using propylphosphonic anhydride as the activator for formic acid, moderate to good yields of the corresponding aldehydes were produced with formic acid as the...

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Autor principal: Wu, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976648/
https://www.ncbi.nlm.nih.gov/pubmed/29849095
http://dx.doi.org/10.1038/s41598-018-26850-2
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author Wu, Xiao-Feng
author_facet Wu, Xiao-Feng
author_sort Wu, Xiao-Feng
collection PubMed
description An interesting palladium-catalyzed carbonylative procedure for the synthesis of aromatic aldehydes from aryl iodides has been developed. By using propylphosphonic anhydride as the activator for formic acid, moderate to good yields of the corresponding aldehydes were produced with formic acid as the carbonyl and hydrogen donors. Interestingly, neither additional phosphine ligand nor inert gas protection is needed here.
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spelling pubmed-59766482018-05-31 Palladium-Catalyzed Synthesis of Aldehydes from Aryl Iodides and Formic acid with Propylphosphonic Anhydride as the Activator Wu, Xiao-Feng Sci Rep Article An interesting palladium-catalyzed carbonylative procedure for the synthesis of aromatic aldehydes from aryl iodides has been developed. By using propylphosphonic anhydride as the activator for formic acid, moderate to good yields of the corresponding aldehydes were produced with formic acid as the carbonyl and hydrogen donors. Interestingly, neither additional phosphine ligand nor inert gas protection is needed here. Nature Publishing Group UK 2018-05-30 /pmc/articles/PMC5976648/ /pubmed/29849095 http://dx.doi.org/10.1038/s41598-018-26850-2 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Wu, Xiao-Feng
Palladium-Catalyzed Synthesis of Aldehydes from Aryl Iodides and Formic acid with Propylphosphonic Anhydride as the Activator
title Palladium-Catalyzed Synthesis of Aldehydes from Aryl Iodides and Formic acid with Propylphosphonic Anhydride as the Activator
title_full Palladium-Catalyzed Synthesis of Aldehydes from Aryl Iodides and Formic acid with Propylphosphonic Anhydride as the Activator
title_fullStr Palladium-Catalyzed Synthesis of Aldehydes from Aryl Iodides and Formic acid with Propylphosphonic Anhydride as the Activator
title_full_unstemmed Palladium-Catalyzed Synthesis of Aldehydes from Aryl Iodides and Formic acid with Propylphosphonic Anhydride as the Activator
title_short Palladium-Catalyzed Synthesis of Aldehydes from Aryl Iodides and Formic acid with Propylphosphonic Anhydride as the Activator
title_sort palladium-catalyzed synthesis of aldehydes from aryl iodides and formic acid with propylphosphonic anhydride as the activator
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976648/
https://www.ncbi.nlm.nih.gov/pubmed/29849095
http://dx.doi.org/10.1038/s41598-018-26850-2
work_keys_str_mv AT wuxiaofeng palladiumcatalyzedsynthesisofaldehydesfromaryliodidesandformicacidwithpropylphosphonicanhydrideastheactivator

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