Baclofen to Prevent Relapse in Gamma-Hydroxybutyrate (GHB)-Dependent Patients: A Multicentre, Open-Label, Non-Randomized, Controlled Trial

BACKGROUND: Gamma-hydroxybutyrate (GHB) dependence is associated with a severe, potentially lethal, withdrawal syndrome and relapse rates as high as 60% within 3 months of detoxification. Baclofen has been shown to decrease self-administration of GHB in mice and reduce relapse in a case series of GH...

Descripción completa

Detalles Bibliográficos
Autores principales: Beurmanjer, Harmen, Kamal, Rama M., de Jong, Cor A. J., Dijkstra, Boukje A. G., Schellekens, Arnt F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976688/
https://www.ncbi.nlm.nih.gov/pubmed/29651711
http://dx.doi.org/10.1007/s40263-018-0516-6

Ejemplares similares

Ejemplares similares