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A Specific Reduction in Aβ(1−42) vs. a Universal Loss of Aβ Peptides in CSF Differentiates Alzheimer's Disease From Meningitis and Multiple Sclerosis
A reduced concentration of Aβ(1−42) in CSF is one of the established biomarkers of Alzheimer's disease. Reduced CSF concentrations of Aβ(1−42) have also been shown in multiple sclerosis, viral encephalitis and bacterial meningitis. As neuroinflammation is one of the neuropathological hallmarks...
Autores principales: | Spitzer, Philipp, Lang, Roland, Oberstein, Timo J., Lewczuk, Piotr, Ermann, Natalia, Huttner, Hagen B., Masouris, Ilias, Kornhuber, Johannes, Ködel, Uwe, Maler, Juan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976781/ https://www.ncbi.nlm.nih.gov/pubmed/29881343 http://dx.doi.org/10.3389/fnagi.2018.00152 |
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