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The Role of TLR4 on PGC-1α-Mediated Oxidative Stress in Tubular Cell in Diabetic Kidney Disease

The role and precise mechanism of TLR4 in mitochondria-related oxidative damage and apoptosis of renal tubules in diabetic kidney disease (DKD) remain unclear. We examined the expression of TLR4 in renal biopsy tissues. Db/db diabetic mice and HK-2 cells cultured under high glucose (HG) were used as...

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Detalles Bibliográficos
Autores principales:	Yuan, Shuguang, Liu, Xuemei, Zhu, Xuejing, Qu, Zhong, Gong, Zailiang, Li, Jun, Xiao, Li, Yang, Yuan, Liu, Hong, Sun, Lin, Liu, Fuyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976914/ https://www.ncbi.nlm.nih.gov/pubmed/29861832 http://dx.doi.org/10.1155/2018/6296802

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