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Leptospirosis in Coastal South India: A Facility Based Study

BACKGROUND: Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries. OBJECTIVE: The present study was designed...

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Autores principales: Holla, Ramesh, Darshan, Bhagwan, Pandey, Latika, Unnikrishnan, Bhaskaran, Kumar, Nithin, Thapar, Rekha, Mithra, Prasanna, Kulkarni, Vaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976951/
https://www.ncbi.nlm.nih.gov/pubmed/29862254
http://dx.doi.org/10.1155/2018/1759125
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author Holla, Ramesh
Darshan, Bhagwan
Pandey, Latika
Unnikrishnan, Bhaskaran
Kumar, Nithin
Thapar, Rekha
Mithra, Prasanna
Kulkarni, Vaman
author_facet Holla, Ramesh
Darshan, Bhagwan
Pandey, Latika
Unnikrishnan, Bhaskaran
Kumar, Nithin
Thapar, Rekha
Mithra, Prasanna
Kulkarni, Vaman
author_sort Holla, Ramesh
collection PubMed
description BACKGROUND: Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries. OBJECTIVE: The present study was designed to assess the sociodemographic characteristics, clinical feature, and outcome of leptospirosis patients. METHODS: This record based retrospective study was conducted in hospitals affiliated to Kasturba Medical College, Mangalore. The registries of the leptospirosis patients during the period of four years between January 2011 and December 2014 were reviewed and the information on demographic and clinical profile of the leptospirosis patients was recorded in the data capture sheet. The information obtained was analyzed using SPSS version 11.5. RESULTS: The study included 202 leptospirosis victims. The mean age of the study population was 40.48 (±14.8) years. Majority of the patients presented with fever (92.1%) at the time of admission. Acute renal failure was found to be the most common complication (79.2%). Case fatality rate was found to be 3.5%. CONCLUSION: High proportion of cases indirectly reflects the endemic nature of the disease in the study setting. The clinical presentation of the leptospirosis is highly protean and may vary from a mild illness to life-threatening complications as evident from the current study.
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spelling pubmed-59769512018-06-03 Leptospirosis in Coastal South India: A Facility Based Study Holla, Ramesh Darshan, Bhagwan Pandey, Latika Unnikrishnan, Bhaskaran Kumar, Nithin Thapar, Rekha Mithra, Prasanna Kulkarni, Vaman Biomed Res Int Research Article BACKGROUND: Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries. OBJECTIVE: The present study was designed to assess the sociodemographic characteristics, clinical feature, and outcome of leptospirosis patients. METHODS: This record based retrospective study was conducted in hospitals affiliated to Kasturba Medical College, Mangalore. The registries of the leptospirosis patients during the period of four years between January 2011 and December 2014 were reviewed and the information on demographic and clinical profile of the leptospirosis patients was recorded in the data capture sheet. The information obtained was analyzed using SPSS version 11.5. RESULTS: The study included 202 leptospirosis victims. The mean age of the study population was 40.48 (±14.8) years. Majority of the patients presented with fever (92.1%) at the time of admission. Acute renal failure was found to be the most common complication (79.2%). Case fatality rate was found to be 3.5%. CONCLUSION: High proportion of cases indirectly reflects the endemic nature of the disease in the study setting. The clinical presentation of the leptospirosis is highly protean and may vary from a mild illness to life-threatening complications as evident from the current study. Hindawi 2018-05-15 /pmc/articles/PMC5976951/ /pubmed/29862254 http://dx.doi.org/10.1155/2018/1759125 Text en Copyright © 2018 Ramesh Holla et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Holla, Ramesh
Darshan, Bhagwan
Pandey, Latika
Unnikrishnan, Bhaskaran
Kumar, Nithin
Thapar, Rekha
Mithra, Prasanna
Kulkarni, Vaman
Leptospirosis in Coastal South India: A Facility Based Study
title Leptospirosis in Coastal South India: A Facility Based Study
title_full Leptospirosis in Coastal South India: A Facility Based Study
title_fullStr Leptospirosis in Coastal South India: A Facility Based Study
title_full_unstemmed Leptospirosis in Coastal South India: A Facility Based Study
title_short Leptospirosis in Coastal South India: A Facility Based Study
title_sort leptospirosis in coastal south india: a facility based study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976951/
https://www.ncbi.nlm.nih.gov/pubmed/29862254
http://dx.doi.org/10.1155/2018/1759125
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