[(18)F]FDG-PET/CT in Hodgkin Lymphoma: Current Usefulness and Perspectives

Functional imaging using 18-fluorodeoxyglycose ([(18)F]FDG) positron emission tomography combined with computed tomography (PET/CT) has become a major imaging modality in Hodgkin lymphoma. This imaging modality allows for a significant improvement in staging, increased sensitivity, which involves di...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanoun, Salim, Rossi, Cedric, Casasnovas, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977118/
https://www.ncbi.nlm.nih.gov/pubmed/29783621
http://dx.doi.org/10.3390/cancers10050145
_version_ 1783327308885524480
author Kanoun, Salim
Rossi, Cedric
Casasnovas, Olivier
author_facet Kanoun, Salim
Rossi, Cedric
Casasnovas, Olivier
author_sort Kanoun, Salim
collection PubMed
description Functional imaging using 18-fluorodeoxyglycose ([(18)F]FDG) positron emission tomography combined with computed tomography (PET/CT) has become a major imaging modality in Hodgkin lymphoma. This imaging modality allows for a significant improvement in staging, increased sensitivity, which involves differentiating residual tumors from fibrosis during assessment, and highly impacts treatment decisions into new PET-driven strategies. This review presents the main scientific data concerning the current applications of [(18)F]FDG-PET/CT in Hodgkin lymphoma at baseline, interim, and the end of treatment evaluation along with the main PET-driven trials for therapeutic decisions. The emergence of total metabolic tumor volume as a new functional prognostic factor will also be discussed.
format Online
Article
Text
id pubmed-5977118
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-59771182018-05-31 [(18)F]FDG-PET/CT in Hodgkin Lymphoma: Current Usefulness and Perspectives Kanoun, Salim Rossi, Cedric Casasnovas, Olivier Cancers (Basel) Review Functional imaging using 18-fluorodeoxyglycose ([(18)F]FDG) positron emission tomography combined with computed tomography (PET/CT) has become a major imaging modality in Hodgkin lymphoma. This imaging modality allows for a significant improvement in staging, increased sensitivity, which involves differentiating residual tumors from fibrosis during assessment, and highly impacts treatment decisions into new PET-driven strategies. This review presents the main scientific data concerning the current applications of [(18)F]FDG-PET/CT in Hodgkin lymphoma at baseline, interim, and the end of treatment evaluation along with the main PET-driven trials for therapeutic decisions. The emergence of total metabolic tumor volume as a new functional prognostic factor will also be discussed. MDPI 2018-05-18 /pmc/articles/PMC5977118/ /pubmed/29783621 http://dx.doi.org/10.3390/cancers10050145 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kanoun, Salim
Rossi, Cedric
Casasnovas, Olivier
[(18)F]FDG-PET/CT in Hodgkin Lymphoma: Current Usefulness and Perspectives
title [(18)F]FDG-PET/CT in Hodgkin Lymphoma: Current Usefulness and Perspectives
title_full [(18)F]FDG-PET/CT in Hodgkin Lymphoma: Current Usefulness and Perspectives
title_fullStr [(18)F]FDG-PET/CT in Hodgkin Lymphoma: Current Usefulness and Perspectives
title_full_unstemmed [(18)F]FDG-PET/CT in Hodgkin Lymphoma: Current Usefulness and Perspectives
title_short [(18)F]FDG-PET/CT in Hodgkin Lymphoma: Current Usefulness and Perspectives
title_sort [(18)f]fdg-pet/ct in hodgkin lymphoma: current usefulness and perspectives
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977118/
https://www.ncbi.nlm.nih.gov/pubmed/29783621
http://dx.doi.org/10.3390/cancers10050145
work_keys_str_mv AT kanounsalim 18ffdgpetctinhodgkinlymphomacurrentusefulnessandperspectives
AT rossicedric 18ffdgpetctinhodgkinlymphomacurrentusefulnessandperspectives
AT casasnovasolivier 18ffdgpetctinhodgkinlymphomacurrentusefulnessandperspectives

Ejemplares similares