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The Most Important Virulence Markers of Yersinia enterocolitica and Their Role during Infection

Yersinia enterocolitica is the causative agent of yersiniosis, a zoonotic disease of growing epidemiological importance with significant consequences for public health. This pathogenic species has been intensively studied for many years. Six biotypes (1A, 1B, 2, 3, 4, 5) and more than 70 serotypes o...

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Autores principales: Bancerz-Kisiel, Agata, Pieczywek, Marta, Łada, Piotr, Szweda, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977175/
https://www.ncbi.nlm.nih.gov/pubmed/29751540
http://dx.doi.org/10.3390/genes9050235
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author Bancerz-Kisiel, Agata
Pieczywek, Marta
Łada, Piotr
Szweda, Wojciech
author_facet Bancerz-Kisiel, Agata
Pieczywek, Marta
Łada, Piotr
Szweda, Wojciech
author_sort Bancerz-Kisiel, Agata
collection PubMed
description Yersinia enterocolitica is the causative agent of yersiniosis, a zoonotic disease of growing epidemiological importance with significant consequences for public health. This pathogenic species has been intensively studied for many years. Six biotypes (1A, 1B, 2, 3, 4, 5) and more than 70 serotypes of Y. enterocolitica have been identified to date. The biotypes of Y. enterocolitica are divided according to their pathogenic properties: the non-pathogenic biotype 1A, weakly pathogenic biotypes 2–5, and the highly pathogenic biotype 1B. Due to the complex pathogenesis of yersiniosis, further research is needed to expand our knowledge of the molecular mechanisms involved in the infection process and the clinical course of the disease. Many factors, both plasmid and chromosomal, significantly influence these processes. The aim of this study was to present the most important virulence markers of Y. enterocolitica and their role during infection.
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spelling pubmed-59771752018-05-31 The Most Important Virulence Markers of Yersinia enterocolitica and Their Role during Infection Bancerz-Kisiel, Agata Pieczywek, Marta Łada, Piotr Szweda, Wojciech Genes (Basel) Review Yersinia enterocolitica is the causative agent of yersiniosis, a zoonotic disease of growing epidemiological importance with significant consequences for public health. This pathogenic species has been intensively studied for many years. Six biotypes (1A, 1B, 2, 3, 4, 5) and more than 70 serotypes of Y. enterocolitica have been identified to date. The biotypes of Y. enterocolitica are divided according to their pathogenic properties: the non-pathogenic biotype 1A, weakly pathogenic biotypes 2–5, and the highly pathogenic biotype 1B. Due to the complex pathogenesis of yersiniosis, further research is needed to expand our knowledge of the molecular mechanisms involved in the infection process and the clinical course of the disease. Many factors, both plasmid and chromosomal, significantly influence these processes. The aim of this study was to present the most important virulence markers of Y. enterocolitica and their role during infection. MDPI 2018-05-03 /pmc/articles/PMC5977175/ /pubmed/29751540 http://dx.doi.org/10.3390/genes9050235 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bancerz-Kisiel, Agata
Pieczywek, Marta
Łada, Piotr
Szweda, Wojciech
The Most Important Virulence Markers of Yersinia enterocolitica and Their Role during Infection
title The Most Important Virulence Markers of Yersinia enterocolitica and Their Role during Infection
title_full The Most Important Virulence Markers of Yersinia enterocolitica and Their Role during Infection
title_fullStr The Most Important Virulence Markers of Yersinia enterocolitica and Their Role during Infection
title_full_unstemmed The Most Important Virulence Markers of Yersinia enterocolitica and Their Role during Infection
title_short The Most Important Virulence Markers of Yersinia enterocolitica and Their Role during Infection
title_sort most important virulence markers of yersinia enterocolitica and their role during infection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977175/
https://www.ncbi.nlm.nih.gov/pubmed/29751540
http://dx.doi.org/10.3390/genes9050235
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