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Influence of Maternal Aging on Mitochondrial Heterogeneity, Inheritance, and Function in Oocytes and Preimplantation Embryos

Contrasting the equal contribution of nuclear genetic material from maternal and paternal sources to offspring, passage of mitochondria, and thus mitochondrial DNA (mtDNA), is uniparental through the egg. Since mitochondria in eggs are ancestral to all somatic mitochondria of the next generation and...

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Detalles Bibliográficos
Autores principales:	Woods, Dori C., Khrapko, Konstantin, Tilly, Jonathan L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977205/ https://www.ncbi.nlm.nih.gov/pubmed/29883421 http://dx.doi.org/10.3390/genes9050265

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