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Attenuated Phenotype and Immunogenic Characteristics of a Mutated Herpes Simplex Virus 1 Strain in the Rhesus Macaque
Herpes simplex virus type 1(HSV-1) presents a conundrum to public health worldwide because of its specific pathogenicity and clinical features. Some experimental vaccines, such as the recombinant viral glycoproteins, exhibit the viral immunogenicity of a host-specific immune response, but none of th...
Autores principales: | Fan, Shengtao, Xu, Xingli, Liao, Yun, Wang, Yongrong, Wang, Jianbin, Feng, Min, Wang, Lichun, Zhang, Ying, He, Zhanlong, Yang, Fengmei, Fraser, Nigel W., Li, Qihan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977227/ https://www.ncbi.nlm.nih.gov/pubmed/29724057 http://dx.doi.org/10.3390/v10050234 |
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