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Clinical importance of eflornithine (α-difluoromethylornithine) for the treatment of malignant gliomas
This review covers the literature between 1989 and 2007 on studies relevant to the neuro-oncology usage of eflornithine (α-difluoromethylornithine), an oral agent that irreversibly inhibits the enzyme ornithine decarboxylase. It covers the use of eflornithine, alone or in combination, to treat high-...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Future Medicine Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977277/ https://www.ncbi.nlm.nih.gov/pubmed/29378419 http://dx.doi.org/10.2217/cns-2017-0031 |