Paper-Based Microfluidic Platforms for Understanding the Role of Exosomes in the Pathogenesis of Major Blindness-Threatening Diseases

Emerging roles of exosomes in the pathogenesis of major blindness-threatening diseases, such as age-related macular degeneration, glaucoma, and corneal dystrophy, were discovered by aqueous humor analysis. A new diagnostic method using cellulose-based devices and microfluidic chip techniques for the...

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Detalles Bibliográficos
Autores principales: Hsu, Min-Yen, Chiu, Chun-Chih, Wang, Juan-Yuan, Huang, Chin-Te, Huang, Yu-Fang, Liou, Jyh-Cheng, Chen, Chihchen, Chen, Hung-Chi, Cheng, Chao-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977324/
https://www.ncbi.nlm.nih.gov/pubmed/29738436
http://dx.doi.org/10.3390/nano8050310
Descripción
Sumario:Emerging roles of exosomes in the pathogenesis of major blindness-threatening diseases, such as age-related macular degeneration, glaucoma, and corneal dystrophy, were discovered by aqueous humor analysis. A new diagnostic method using cellulose-based devices and microfluidic chip techniques for the isolation of exosomes from aqueous humor is less cumbersome and saves time. This method will enable more investigations for aqueous humor analysis in the future.

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