Paper-Based Microfluidic Platforms for Understanding the Role of Exosomes in the Pathogenesis of Major Blindness-Threatening Diseases

Emerging roles of exosomes in the pathogenesis of major blindness-threatening diseases, such as age-related macular degeneration, glaucoma, and corneal dystrophy, were discovered by aqueous humor analysis. A new diagnostic method using cellulose-based devices and microfluidic chip techniques for the...

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Autores principales: Hsu, Min-Yen, Chiu, Chun-Chih, Wang, Juan-Yuan, Huang, Chin-Te, Huang, Yu-Fang, Liou, Jyh-Cheng, Chen, Chihchen, Chen, Hung-Chi, Cheng, Chao-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977324/
https://www.ncbi.nlm.nih.gov/pubmed/29738436
http://dx.doi.org/10.3390/nano8050310
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author Hsu, Min-Yen
Chiu, Chun-Chih
Wang, Juan-Yuan
Huang, Chin-Te
Huang, Yu-Fang
Liou, Jyh-Cheng
Chen, Chihchen
Chen, Hung-Chi
Cheng, Chao-Min
author_facet Hsu, Min-Yen
Chiu, Chun-Chih
Wang, Juan-Yuan
Huang, Chin-Te
Huang, Yu-Fang
Liou, Jyh-Cheng
Chen, Chihchen
Chen, Hung-Chi
Cheng, Chao-Min
author_sort Hsu, Min-Yen
collection PubMed
description Emerging roles of exosomes in the pathogenesis of major blindness-threatening diseases, such as age-related macular degeneration, glaucoma, and corneal dystrophy, were discovered by aqueous humor analysis. A new diagnostic method using cellulose-based devices and microfluidic chip techniques for the isolation of exosomes from aqueous humor is less cumbersome and saves time. This method will enable more investigations for aqueous humor analysis in the future.
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spelling pubmed-59773242018-06-05 Paper-Based Microfluidic Platforms for Understanding the Role of Exosomes in the Pathogenesis of Major Blindness-Threatening Diseases Hsu, Min-Yen Chiu, Chun-Chih Wang, Juan-Yuan Huang, Chin-Te Huang, Yu-Fang Liou, Jyh-Cheng Chen, Chihchen Chen, Hung-Chi Cheng, Chao-Min Nanomaterials (Basel) Commentary Emerging roles of exosomes in the pathogenesis of major blindness-threatening diseases, such as age-related macular degeneration, glaucoma, and corneal dystrophy, were discovered by aqueous humor analysis. A new diagnostic method using cellulose-based devices and microfluidic chip techniques for the isolation of exosomes from aqueous humor is less cumbersome and saves time. This method will enable more investigations for aqueous humor analysis in the future. MDPI 2018-05-08 /pmc/articles/PMC5977324/ /pubmed/29738436 http://dx.doi.org/10.3390/nano8050310 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Commentary
Hsu, Min-Yen
Chiu, Chun-Chih
Wang, Juan-Yuan
Huang, Chin-Te
Huang, Yu-Fang
Liou, Jyh-Cheng
Chen, Chihchen
Chen, Hung-Chi
Cheng, Chao-Min
Paper-Based Microfluidic Platforms for Understanding the Role of Exosomes in the Pathogenesis of Major Blindness-Threatening Diseases
title Paper-Based Microfluidic Platforms for Understanding the Role of Exosomes in the Pathogenesis of Major Blindness-Threatening Diseases
title_full Paper-Based Microfluidic Platforms for Understanding the Role of Exosomes in the Pathogenesis of Major Blindness-Threatening Diseases
title_fullStr Paper-Based Microfluidic Platforms for Understanding the Role of Exosomes in the Pathogenesis of Major Blindness-Threatening Diseases
title_full_unstemmed Paper-Based Microfluidic Platforms for Understanding the Role of Exosomes in the Pathogenesis of Major Blindness-Threatening Diseases
title_short Paper-Based Microfluidic Platforms for Understanding the Role of Exosomes in the Pathogenesis of Major Blindness-Threatening Diseases
title_sort paper-based microfluidic platforms for understanding the role of exosomes in the pathogenesis of major blindness-threatening diseases
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977324/
https://www.ncbi.nlm.nih.gov/pubmed/29738436
http://dx.doi.org/10.3390/nano8050310
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