Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways

BACKGROUND: The increasing genomic complexity of acute myeloid leukemia (AML), the most common form of acute leukemia, poses a major challenge to its therapy. To identify potent therapeutic targets with the ability to block multiple cancer-driving pathways is thus imperative. The unique peptidyl-pro...

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Detalles Bibliográficos
Autores principales: Lian, Xiaolan, Lin, Yu-Min, Kozono, Shingo, Herbert, Megan K., Li, Xin, Yuan, Xiaohong, Guo, Jiangrui, Guo, Yafei, Tang, Min, Lin, Jia, Huang, Yiping, Wang, Bixin, Qiu, Chenxi, Tsai, Cheng-Yu, Xie, Jane, Cao, Ziang Jeff, Wu, Yong, Liu, Hekun, Zhou, Xiaozhen, Lu, Kunping, Chen, Yuanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977460/
https://www.ncbi.nlm.nih.gov/pubmed/29848341
http://dx.doi.org/10.1186/s13045-018-0611-7

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