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miR-10a rejuvenates aged human mesenchymal stem cells and improves heart function after myocardial infarction through KLF4

BACKGROUND: Aging is one of the key factors that regulate the function of human bone marrow mesenchymal stem cells (hBM-MSCs) and related changes in microRNA (miRNA) expression. However, data reported on aging-related miRNA changes in hBM-MSCs are limited. METHODS: We demonstrated previously that mi...

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Detalles Bibliográficos
Autores principales:	Dong, Jun, Zhang, Zhenhui, Huang, Hongshen, Mo, Pei, Cheng, Chuanfan, Liu, Jianwei, Huang, Weizhao, Tian, Chaowei, Zhang, Chongyu, Li, Jiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977543/ https://www.ncbi.nlm.nih.gov/pubmed/29848383 http://dx.doi.org/10.1186/s13287-018-0895-0

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