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Hepatic infarction induced by HELLP syndrome: a case report and review of the literature

BACKGROUND: HELLP syndrome is a rare disease in China, and 20% of patients with severe preeclampsia have been accompanied with HELLP syndrome, which is characterized by the presence of hemolysis, elevated liver enzymes and low platelet count. CASE PRESENTATION: In this case, we reported that a patie...

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Autores principales: Guo, Qinyue, Yang, Zhengfei, Guo, Jian, Zhang, Lei, Gao, Lan, Zhou, Bo, Shi, Qindong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977550/
https://www.ncbi.nlm.nih.gov/pubmed/29848304
http://dx.doi.org/10.1186/s12884-018-1799-9
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author Guo, Qinyue
Yang, Zhengfei
Guo, Jian
Zhang, Lei
Gao, Lan
Zhou, Bo
Shi, Qindong
author_facet Guo, Qinyue
Yang, Zhengfei
Guo, Jian
Zhang, Lei
Gao, Lan
Zhou, Bo
Shi, Qindong
author_sort Guo, Qinyue
collection PubMed
description BACKGROUND: HELLP syndrome is a rare disease in China, and 20% of patients with severe preeclampsia have been accompanied with HELLP syndrome, which is characterized by the presence of hemolysis, elevated liver enzymes and low platelet count. CASE PRESENTATION: In this case, we reported that a patient with preeclampsia was diagnosed with HELLP syndrome. Furthermore, hepatic infarction also was found via the computed tomographic (CT) images, which showed peripheral wedge-shaped inhomogeneous low attenuation in the right hepatic lobes via plain CT scan, and the low-density shadow and mottled appearance in the same areas where vessels were seen coursing through them via contrast-enhanced CT scan. CONCLUSIONS: Besides typical clinical manifestations of the pregnant patient with preeclampsia, the typical laboratory evidences were elevated liver enzymes and thrombocytopenia. The abdominal CT scan showed imaging features of hepatic infarction, which was helpful to identify the rare complication of HELLP syndrome. Thus, we diagnosed a patient with HELLP syndrome with hepatic infarction, though the patient had no chance to do the liver biopsy.
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spelling pubmed-59775502018-06-06 Hepatic infarction induced by HELLP syndrome: a case report and review of the literature Guo, Qinyue Yang, Zhengfei Guo, Jian Zhang, Lei Gao, Lan Zhou, Bo Shi, Qindong BMC Pregnancy Childbirth Case Report BACKGROUND: HELLP syndrome is a rare disease in China, and 20% of patients with severe preeclampsia have been accompanied with HELLP syndrome, which is characterized by the presence of hemolysis, elevated liver enzymes and low platelet count. CASE PRESENTATION: In this case, we reported that a patient with preeclampsia was diagnosed with HELLP syndrome. Furthermore, hepatic infarction also was found via the computed tomographic (CT) images, which showed peripheral wedge-shaped inhomogeneous low attenuation in the right hepatic lobes via plain CT scan, and the low-density shadow and mottled appearance in the same areas where vessels were seen coursing through them via contrast-enhanced CT scan. CONCLUSIONS: Besides typical clinical manifestations of the pregnant patient with preeclampsia, the typical laboratory evidences were elevated liver enzymes and thrombocytopenia. The abdominal CT scan showed imaging features of hepatic infarction, which was helpful to identify the rare complication of HELLP syndrome. Thus, we diagnosed a patient with HELLP syndrome with hepatic infarction, though the patient had no chance to do the liver biopsy. BioMed Central 2018-05-30 /pmc/articles/PMC5977550/ /pubmed/29848304 http://dx.doi.org/10.1186/s12884-018-1799-9 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Guo, Qinyue
Yang, Zhengfei
Guo, Jian
Zhang, Lei
Gao, Lan
Zhou, Bo
Shi, Qindong
Hepatic infarction induced by HELLP syndrome: a case report and review of the literature
title Hepatic infarction induced by HELLP syndrome: a case report and review of the literature
title_full Hepatic infarction induced by HELLP syndrome: a case report and review of the literature
title_fullStr Hepatic infarction induced by HELLP syndrome: a case report and review of the literature
title_full_unstemmed Hepatic infarction induced by HELLP syndrome: a case report and review of the literature
title_short Hepatic infarction induced by HELLP syndrome: a case report and review of the literature
title_sort hepatic infarction induced by hellp syndrome: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977550/
https://www.ncbi.nlm.nih.gov/pubmed/29848304
http://dx.doi.org/10.1186/s12884-018-1799-9
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