Cargando…
Characteristic profiles of DNA epigenetic modifications in colon cancer and its predisposing conditions—benign adenomas and inflammatory bowel disease
BACKGROUND: Active demethylation of 5-methyl-2′-deoxycytidine (5-mdC) in DNA occurs by oxidation to 5-(hydroxymethyl)-2′-deoxycytidine (5-hmdC) and further oxidation to 5-formyl-2′-deoxycytidine (5-fdC) and 5-carboxy-2′-deoxycytidine (5-cadC), and is carried out by enzymes of the ten-eleven transloc...
Autores principales: | Dziaman, Tomasz, Gackowski, Daniel, Guz, Jolanta, Linowiecka, Kinga, Bodnar, Magdalena, Starczak, Marta, Zarakowska, Ewelina, Modrzejewska, Martyna, Szpila, Anna, Szpotan, Justyna, Gawronski, Maciej, Labejszo, Anna, Liebert, Ariel, Banaszkiewicz, Zbigniew, Klopocka, Maria, Foksinski, Marek, Marszalek, Andrzej, Olinski, Ryszard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977551/ https://www.ncbi.nlm.nih.gov/pubmed/29875879 http://dx.doi.org/10.1186/s13148-018-0505-0 |
Ejemplares similares
-
In vivo evidence of ascorbate involvement in the generation of epigenetic DNA modifications in leukocytes from patients with colorectal carcinoma, benign adenoma and inflammatory bowel disease
por: Starczak, Marta, et al.
Publicado: (2018) -
The urinary excretion of epigenetically modified DNA as a marker of pediatric ALL status and chemotherapy response
por: Rozalski, Rafal, et al.
Publicado: (2021) -
Tissue-Specific Differences in DNA Modifications (5-Hydroxymethylcytosine, 5-Formylcytosine, 5-Carboxylcytosine and 5-Hydroxymethyluracil) and Their Interrelationships
por: Gackowski, Daniel, et al.
Publicado: (2015) -
Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines
por: Foksinski, Marek, et al.
Publicado: (2017) -
Correction: Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines
por: Foksinski, Marek, et al.
Publicado: (2018)