Transcription factor motif enrichment in whole transcriptome analysis identifies STAT4 and BCL6 as the most prominent binding motif in systemic juvenile idiopathic arthritis

BACKGROUND: The term systemic juvenile idiopathic arthritis (sJIA) describes an autoinflammatory condition characterized by arthritis and severe systemic inflammation, which in later stages can transform into interleukin (IL)-17-driven autoimmune arthritis. IL-1 antagonists have been used with good...

Descripción completa

Detalles Bibliográficos
Autores principales: Hügle, Boris, Schippers, Anastasia, Fischer, Nadine, Ohl, Kim, Denecke, Bernd, Ticconi, Fabio, Vastert, Bas, Costa, Ivan G., Haas, Johannes-Peter, Tenbrock, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977738/
https://www.ncbi.nlm.nih.gov/pubmed/29848367
http://dx.doi.org/10.1186/s13075-018-1603-2

Ejemplares similares

Ejemplares similares