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IFI44L is a novel tumor suppressor in human hepatocellular carcinoma affecting cancer stemness, metastasis, and drug resistance via regulating met/Src signaling pathway
BACKGROUND: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. The disease recurrent rate is relatively high resulted in poor 5-year survival in advanced HCC. Cancer stem cells (CSCs) have been considered to be one of the main mechanisms for chemoresistance...
Autores principales: | Huang, Wei-Chieh, Tung, Shiao-Lin, Chen, Yao-Li, Chen, Po-Ming, Chu, Pei-Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977745/ https://www.ncbi.nlm.nih.gov/pubmed/29848298 http://dx.doi.org/10.1186/s12885-018-4529-9 |
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