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Study on the Mechanism of Cell Cycle Checkpoint Kinase 2 (CHEK2) Gene Dysfunction in Chemotherapeutic Drug Resistance of Triple Negative Breast Cancer Cells

BACKGROUND: This study aimed to investigate the mechanism of CHEK2 gene dysfunction in drug resistance of triple negative breast cancer (TNBC) cells. MATERIAL/METHODS: To perform our study, a stable CHEK2 wild type (CHEK2 WT) or CHEK2 Y390C mutation (CHEK2 Y390C) expressed MDA-MB-231 cell line was e...

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Detalles Bibliográficos
Autores principales:	Luo, Li, Gao, Wei, Wang, Jinghui, Wang, Dingxue, Peng, Xiaobo, Jia, Zhaoyang, Jiang, Ye, Li, Gongzhuo, Tang, Dongxin, Wang, Yajie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978023/ https://www.ncbi.nlm.nih.gov/pubmed/29761796 http://dx.doi.org/10.12659/MSM.907256

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