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Synergistic Inhibition of Thalidomide and Icotinib on Human Non-Small Cell Lung Carcinomas Through ERK and AKT Signaling

BACKGROUND: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have been widely used in the treatment of non-small cell lung cancer (NSCLC) patients with sensitive EGFR mutations. However, the survival of patients with EGFR-TKI administration is limited by the inevitable develop...

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Detalles Bibliográficos
Autores principales: Sun, Xiang, Xu, Yang, Wang, Yi, Chen, Qian, Liu, Liu, Bao, Yangyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978026/
https://www.ncbi.nlm.nih.gov/pubmed/29763936
http://dx.doi.org/10.12659/MSM.909977