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Foretinib (GSK1363089) induces p53-dependent apoptosis in endometrial cancer

OBJECTIVE: Foretinib (GSK1363089 or XL880), which is an oral multikinase inhibitor developed to primarily target the hepatocyte growth factor (HGF)/Met signaling pathway, has shown anti-tumor effects against some cancers in preclinical and clinical studies. RESULTS: HGF/Met signaling in endometrial...

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Detalles Bibliográficos
Autores principales:	Kogata, Yuhei, Tanaka, Tomohito, Ono, Yoshihiro J., Hayashi, Masami, Terai, Yoshito, Ohmichi, Masahide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978264/ https://www.ncbi.nlm.nih.gov/pubmed/29854314 http://dx.doi.org/10.18632/oncotarget.25232

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