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Inhibition of the Activin Receptor Type-2B Pathway Restores Regenerative Capacity in Satellite Cell-Depleted Skeletal Muscle

Degenerative myopathies typically display a decline in satellite cells coupled with a replacement of muscle fibers by fat and fibrosis. During this pathological remodeling, satellite cells are present at lower numbers and do not display a proper regenerative function. Whether a decline in satellite...

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Detalles Bibliográficos
Autores principales: Formicola, Luigi, Pannérec, Alice, Correra, Rosa Maria, Gayraud-Morel, Barbara, Ollitrault, David, Besson, Vanessa, Tajbakhsh, Shahragim, Lachey, Jennifer, Seehra, Jasbir S., Marazzi, Giovanna, Sassoon, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978452/
https://www.ncbi.nlm.nih.gov/pubmed/29881353
http://dx.doi.org/10.3389/fphys.2018.00515