Cargando…
Inhibition of the Activin Receptor Type-2B Pathway Restores Regenerative Capacity in Satellite Cell-Depleted Skeletal Muscle
Degenerative myopathies typically display a decline in satellite cells coupled with a replacement of muscle fibers by fat and fibrosis. During this pathological remodeling, satellite cells are present at lower numbers and do not display a proper regenerative function. Whether a decline in satellite...
Autores principales: | Formicola, Luigi, Pannérec, Alice, Correra, Rosa Maria, Gayraud-Morel, Barbara, Ollitrault, David, Besson, Vanessa, Tajbakhsh, Shahragim, Lachey, Jennifer, Seehra, Jasbir S., Marazzi, Giovanna, Sassoon, David A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978452/ https://www.ncbi.nlm.nih.gov/pubmed/29881353 http://dx.doi.org/10.3389/fphys.2018.00515 |
Ejemplares similares
-
P992: A MODIFIED ACTIVIN RECEPTOR TYPE II LIGAND TRAP RKER-050 RESTORED ERYTHROPOIESIS IN A MOUSE MODEL OF MYELOFIBROSIS
por: Moses, Blake, et al.
Publicado: (2023) -
The imprinted gene Pw1/Peg3 regulates skeletal muscle growth, satellite cell metabolic state, and self-renewal
por: Correra, Rosa Maria, et al.
Publicado: (2018) -
The extraocular muscle stem cell niche is resistant to ageing and disease
por: Formicola, Luigi, et al.
Publicado: (2014) -
P1488: COMBINING ALK2 INHIBITION WITH A MODIFIED ACTIVIN RECEPTOR IIA LIGAND TRAP PROVIDED ADDITIVE BENEFITS IN RESOLVING ANEMIA IN A MOUSE MODEL OF ANEMIA OF INFLAMMATION
por: Wang, Chia-Yu, et al.
Publicado: (2023) -
Small-RNA sequencing identifies dynamic microRNA deregulation during skeletal muscle lineage progression
por: Castel, David, et al.
Publicado: (2018)