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Normal tissue doses from MV image‐guided radiation therapy (IGRT) using orthogonal MV and MV‐CBCT

PURPOSE: The aim of this study was to measure and compare the mega‐voltage imaging dose from the Halcyon medical linear accelerator (Varian Medical Systems) with measured imaging doses with the dose calculated by Eclipse treatment planning system. METHODS: An anthropomorphic thorax phantom was image...

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Autores principales: Li, Yuting, Netherton, Tucker, Nitsch, Paige L., Balter, Peter A., Gao, Song, Klopp, Ann H., Court, Laurence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978715/
https://www.ncbi.nlm.nih.gov/pubmed/29500856
http://dx.doi.org/10.1002/acm2.12276
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author Li, Yuting
Netherton, Tucker
Nitsch, Paige L.
Balter, Peter A.
Gao, Song
Klopp, Ann H.
Court, Laurence E.
author_facet Li, Yuting
Netherton, Tucker
Nitsch, Paige L.
Balter, Peter A.
Gao, Song
Klopp, Ann H.
Court, Laurence E.
author_sort Li, Yuting
collection PubMed
description PURPOSE: The aim of this study was to measure and compare the mega‐voltage imaging dose from the Halcyon medical linear accelerator (Varian Medical Systems) with measured imaging doses with the dose calculated by Eclipse treatment planning system. METHODS: An anthropomorphic thorax phantom was imaged using all imaging techniques available with the Halcyon linac — MV cone‐beam computed tomography (MV‐CBCT) and orthogonal anterior‐posterior/lateral pairs (MV‐MV), both with high‐quality and low‐dose modes. In total, 54 imaging technique, isocenter position, and field size combinations were evaluated. The imaging doses delivered to 11 points in the phantom (in‐target and extra‐target) were measured using an ion chamber, and compared with the imaging doses calculated using Eclipse. RESULTS: For high‐quality MV‐MV mode, the mean extra‐target doses delivered to the heart, left lung, right lung and spine were 1.18, 1.64, 0.80, and 1.11 cGy per fraction, respectively. The corresponding mean in‐target doses were 3.36, 3.72, 2.61, and 2.69 cGy per fraction, respectively. For MV‐MV technique, the extra‐target imaging dose had greater variation and dependency on imaging field size than did the in‐target dose. Compared to MV‐MV technique, the imaging dose from MV‐CBCT was less sensitive to the location of the organ relative to the treatment field. For high‐quality MV‐CBCT mode, the mean imaging doses to the heart, left lung, right lung, and spine were 8.45, 7.16, 7.19, and 6.51 cGy per fraction, respectively. For both MV‐MV and MV‐CBCT techniques, the low‐dose mode resulted in an imaging dose about half of that in high‐quality mode. CONCLUSION: The in‐target doses due to MV imaging using the Halcyon ranged from 0.59 to 9.75 cGy, depending on the choice of imaging technique. Extra‐target doses from MV‐MV technique ranged from 0 to 2.54 cGy. The MV imaging dose was accurately calculated by Eclipse, with maximum differences less than 0.5% of a typical treatment dose (assuming a 60 Gy prescription). Therefore, the cumulative imaging and treatment plan dose distribution can be expected to accurately reflect the actual dose.
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spelling pubmed-59787152018-06-01 Normal tissue doses from MV image‐guided radiation therapy (IGRT) using orthogonal MV and MV‐CBCT Li, Yuting Netherton, Tucker Nitsch, Paige L. Balter, Peter A. Gao, Song Klopp, Ann H. Court, Laurence E. J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: The aim of this study was to measure and compare the mega‐voltage imaging dose from the Halcyon medical linear accelerator (Varian Medical Systems) with measured imaging doses with the dose calculated by Eclipse treatment planning system. METHODS: An anthropomorphic thorax phantom was imaged using all imaging techniques available with the Halcyon linac — MV cone‐beam computed tomography (MV‐CBCT) and orthogonal anterior‐posterior/lateral pairs (MV‐MV), both with high‐quality and low‐dose modes. In total, 54 imaging technique, isocenter position, and field size combinations were evaluated. The imaging doses delivered to 11 points in the phantom (in‐target and extra‐target) were measured using an ion chamber, and compared with the imaging doses calculated using Eclipse. RESULTS: For high‐quality MV‐MV mode, the mean extra‐target doses delivered to the heart, left lung, right lung and spine were 1.18, 1.64, 0.80, and 1.11 cGy per fraction, respectively. The corresponding mean in‐target doses were 3.36, 3.72, 2.61, and 2.69 cGy per fraction, respectively. For MV‐MV technique, the extra‐target imaging dose had greater variation and dependency on imaging field size than did the in‐target dose. Compared to MV‐MV technique, the imaging dose from MV‐CBCT was less sensitive to the location of the organ relative to the treatment field. For high‐quality MV‐CBCT mode, the mean imaging doses to the heart, left lung, right lung, and spine were 8.45, 7.16, 7.19, and 6.51 cGy per fraction, respectively. For both MV‐MV and MV‐CBCT techniques, the low‐dose mode resulted in an imaging dose about half of that in high‐quality mode. CONCLUSION: The in‐target doses due to MV imaging using the Halcyon ranged from 0.59 to 9.75 cGy, depending on the choice of imaging technique. Extra‐target doses from MV‐MV technique ranged from 0 to 2.54 cGy. The MV imaging dose was accurately calculated by Eclipse, with maximum differences less than 0.5% of a typical treatment dose (assuming a 60 Gy prescription). Therefore, the cumulative imaging and treatment plan dose distribution can be expected to accurately reflect the actual dose. John Wiley and Sons Inc. 2018-03-03 /pmc/articles/PMC5978715/ /pubmed/29500856 http://dx.doi.org/10.1002/acm2.12276 Text en © 2018 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Li, Yuting
Netherton, Tucker
Nitsch, Paige L.
Balter, Peter A.
Gao, Song
Klopp, Ann H.
Court, Laurence E.
Normal tissue doses from MV image‐guided radiation therapy (IGRT) using orthogonal MV and MV‐CBCT
title Normal tissue doses from MV image‐guided radiation therapy (IGRT) using orthogonal MV and MV‐CBCT
title_full Normal tissue doses from MV image‐guided radiation therapy (IGRT) using orthogonal MV and MV‐CBCT
title_fullStr Normal tissue doses from MV image‐guided radiation therapy (IGRT) using orthogonal MV and MV‐CBCT
title_full_unstemmed Normal tissue doses from MV image‐guided radiation therapy (IGRT) using orthogonal MV and MV‐CBCT
title_short Normal tissue doses from MV image‐guided radiation therapy (IGRT) using orthogonal MV and MV‐CBCT
title_sort normal tissue doses from mv image‐guided radiation therapy (igrt) using orthogonal mv and mv‐cbct
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978715/
https://www.ncbi.nlm.nih.gov/pubmed/29500856
http://dx.doi.org/10.1002/acm2.12276
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